OLIVER LABORATORY

Douglas L. Oliver, Ph.D.

SYNAPTIC ORGANIZATION OF THE AUDITORY SYSTEM Department of Neuroscience http://www.uchc.edu/ Farmington, CT 06030-3401 Fax: (860) 679-8766 Email: doliver@neuron.uchc.edu Main Neurocytology Lab - L-4039; 679-2549 Physiology Lab - L-4038; 679-3559 Graphics Lab - L-4062; 679-7644 Oliver Office - L-4043; 679-2241

Lab Picture Gallery Movie Gallery Slides TEACHING: MEDS 384 Mammalian Neuroanatomy Organ Systems 1 (neuroscience for medical and dental students) LAB MEMBERS: Tetsufumi Ito , PhD Visiting Assistant Professor University of Fukui , Japan tito@neuron.uchc.edu Hye-Sook Ahn Postdoctoral Fellow ahn@uchc.edu Deborah Bishop, Research Associate bishop@neuron.uchc.edu William Loftus, Ph.D. Instructor loftus@neuron.uchc.edu LAB MEMBERS OF THE PAST

RESEARCH INTERESTS A Discontinuous Tonotopic Organization in the Inferior Colliculus. There is a defined space of tissue devoted to a given frequency bandwidth. The Cytoarchitecture of the Inferior Colliculus Revisited: A Common Organization of the Lateral Cortex. Neuronal responses to lemniscal stimulation in laminar brain slices of the inferior colliculus. New ways to study synaptic stimulation and microcircuitry in the inferior colliculus. Granule cells in cochlear nucleus activated by sound. Sound activation is detected by FOS protein expression. Laminar inputs from dorsal cochlear nucleus and ventral cochlear nucleus to the central nucleus of the inferior colliculus: Two patterns of convergence. Acoustic environment determines phosphorylation state of the Kv3.1 potassium channel in auditory neurons. GABA-A Synapses Shape Neuronal Responses to Sound Intensity in the Inferior Colliculus. Organization of Binaural Excitatory and Inhibitory Inputs to the Inferior Colliculus from the Superior Olive. Each frequency-band lamina in the inferior colliculus may comprise several functional modules with different combinations of inputs. Topography of ITD Coding in Projections of Medial Superior Olive to Inferior Colliculus. The representation of sound location along the azimuth in the inferior colliculus most likely relies on a complex, non-linear map. Direct projections from the cochlear nucleus to the medial geniculate body. A multi-modal parallel pathway? Synaptic modification in neurons of the central nucleus of the inferior colliculus. We show LTP in the inferior colliculus. Cell types in inferior colliculus defined by ionic currents. New neuron types are based on unique K+ and Ca++ currents discovered in brain slice experiments.